Solicitation # DARPA-PS-26-129Updated Aug 21, 2026
This RFP closed on Oct 19, 2026.
Oct 19, 2026
Responses were due Oct 19, 2026, 4:00 PM EDT
Same NAICS group or Research & Scientific Services, nearby first, ranked by score.
Department of the Air Force · Washington, DC
Why this score
34 days to respond, active buyer ($36.7B FY24–FY26).
Department of the Air Force · Langley AFB, VA
Why this score
Active buyer ($36.7B FY24–FY26), 137 days to respond.
National Geospatial-Intelligence Agency (NGA)
Why this score
38 days to respond, active buyer ($98.2B FY24–FY26).
Department of the Air Force
Why this score
Active buyer ($36.7B FY24–FY26), well documented (5 files).
Department of the Air Force
Why this score
Active buyer ($36.7B FY24–FY26), well documented (7 files).
Department of the Air Force
Why this score
Active buyer ($36.7B FY24–FY26), well documented (5 files).
RFP Detector Scores are informational.How we score →
Summary by RFP Detector
Defense Advanced Research Projects Agency (DARPA) (Def Advanced Research Projects Agcy), part of the Department of Defense, posted a solicitation titled “Protein ENGineering (PENG)” under solicitation number DARPA-PS-26-129. It was first posted on Aug 7, 2026 and has been updated once since. The response deadline was Oct 19, 2026, 4:00 PM EDT. It is classified under NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)) and product/service code AC12. No set-aside is listed. The listed point of contact is BAA Coordinator.
Score at publication
Every RFP starts at 50. Each factor adds or subtracts points compared with a typical RFP; unknown data counts as neutral.
Frozen at publication: closed RFPs are not re-scored.
Starts at 50
No value published. Typical award is about $1.7M: the median of 37 DARPA contracts over $25K awarded in NAICS 541714, FY24–FY26.
Full and open competition. The largest recipient took 21% of these dollars in FY24–FY26.
DARPA obligated $140M on NAICS 541714 across 37 contracts in FY24–FY26. 53 other notices from this office in the past 12 months.
Solicitation, bids due: 73 days to respond (due Oct 19, 2026, 4:00 PM EDT). Long lead time.
Documents not listed, named contact with email, 138-word description.
Posted today.
50 + contributions = 72 (B, Strong)
Informational, not advice to bid or not bid. Score version 1.0.0, evaluated Aug 7, 2026.
Eligibility · Full and open competition
Full and open competition means the notice states no set-aside: any responsible business can respond, subject to the requirements in the notice.
Not stated in a form we could extract. See the official solicitation for requirements, evaluation criteria and submission steps.
From the official notice
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals for the development of a multifunctional, target-agnostic platform for precise, programmable editing of endogenous proteins. The goal of the Protein ENGineering (PENG) program is to transition proteome engineering from a collection of isolated, bespoke tools into a universal, software-defined discipline. The PENG program will establish a comprehensive, integrated platform composed of modular targeting, generalizable effector chemistries, and multiplexed control systems. Rather than developing isolated, target-specific tools, performers will integrate novel splicing, ligation, and co-translational techniques to directly recognize, modify, and rewrite endogenous proteins within complex biological architectures. Performers may explore multiple technical paths, progressively advancing their approaches from foundational validation to robust demonstrations of efficacy. Ultimately, this integrated platform will be validated in high-fidelity cellular models (e.g., organoids), to provide an integrated proof-of-concept at the tissue level.
No documents are listed for this notice.
BAA Coordinator
PrimaryPoints of contact as published on the notice.
Solicitation posted
Solicitation posted
Responses were due
Federal award history
Defense Advanced Research Projects Agency · NAICS 541714 · FY24–FY26
Recipients of past awards in this market, not the incumbent of this RFP.
| Fiscal year | Obligated ($) |
|---|---|
| FY2022 | 65,224,450.95 |
| FY2023 | 49,389,555.26 |
| FY2024 | 64,000,905.2 |
| FY2025 | 60,492,555.91 |
| FY2026 | 15,893,063.64 |
Federal contract award records, award types A–D, FY24–FY26. Updated Nov 13, 2026.
32 open RFPs from this issuer and its offices.
Defense Advanced Research Projects Agency (DARPA)
Why this score
Typical award ~$1.7M; but only 2 days left.
Defense Advanced Research Projects Agency (DARPA)
Why this score
Typical award ~$1.8M, active buyer ($3.2B FY24–FY26); but thin documentation.
Defense Advanced Research Projects Agency (DARPA)
Why this score
Typical award ~$1.8M, active buyer ($3.2B FY24–FY26); but limited documentation.
Defense Advanced Research Projects Agency (DARPA)
Why this score
Active issuer (53 RFPs); but posted 162 days ago.
Defense Advanced Research Projects Agency (DARPA)
Why this score
16 days to respond, typical award ~$1.8M; but posted 249 days ago.
RFP Detector Scores are informational.How we score →
Official federal notice. Updated Aug 21, 2026.
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